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IMRE seminar on "Self Assembly of Pore Forming Toxins and Kinetic Pathways in Lipid Bilayers"
27 Oct 14 (Mon) - 11.00am - 12.00pm
Pore forming toxins are protein molecules that have evolved to form unregulated pores on the cell membrane leading to osmotic stress and lysis. These water soluble proteins bind to lipid membranes and following a process of self assembly at the membrane interface form nanometer sized pores. Although pore forming toxins have been extensively studied, the molecular mechanisms of the oligomerization pathways and the fate of lipids during the final stages of pore formation are incompletely understood. Using a combination of experimental and molecular dynamics simulations we study the pore forming mechanism for the Cytolysin A pore forming toxin.

IMRE seminar on "Advanced Nano-manufacturing Techniques : Combining Top Down and Bottom Up Approaches"
28 Oct 14 (Tue) - 10.00am - 11.00am
Progress in nanosciences and nanotechnology requires nano manufacturing technologies and materials which enable some kind of hybrid functionality. Physical nano structuring has demonstrated added value surfaces which could be used in numerous modern applications and products. In this talk, we will discuss how to utilize advanced nanoimprint based manufacturing processes to mass replicate nano metric scale structures and debate the use of step and repeat imprinting methods in order to upscale nano structures by combining top down and bottom up approaches.

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